Twentyone Hotel | Hotel in Prati, Rome

Prati mornings, rooftop light, breakfast room, city view.
Located in Little Italy, Kasa Little Italy puts the neighborhood’s cafes, galleries, and waterfront right outside the door. Amtrak’s Santa Fe Depot is a 6-minute walk away, San Diego International is a quick 7-minute drive, and the USS Midway Museum is just 9 minutes from your suite.Once you get back, unwind on the balcony most units feature, or head down to the pool and fitness center for a change of scenery. Every suite comes with free WiFi, a flat-screen TV, and cashless, contactless self check-in via the virtual front desk. A private bathroom, single-room air conditioning, and a full kitchen are featured in every 42–91 m² suite or studio. King beds furnish the 1-bedroom suites, while studios pair a queen with a sofa bed, and select studios add a soaking bathtub. Full toiletries are stocked throughout, and thanks to the in-unit washer and dryer, you’ll be able to travel light.
24-hour front desk, air conditioning, Castel Sant'Angelo 10-minute walk away

- Arrival
- Minimum age for check-in: 18
- Design
- Modern boutique hotel, minimalist rooms
- Bath products
- Toiletries, Wheelchair accessible
- Tech
- Free WiFi · LCD satellite TV · Air conditioning
Minimalist rooms with air conditioning and soundproofing
A fitness center, city views, and breakfast on the roof
Twentyone Hotel Reviews
Great place to stay in a convenient position in Rome
Good to know · before you book.
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Frequently asked questions
Yes. Parking is available on site, including a parking garage and private parking. Spaces are limited and subject to availability.
Yes. A breakfast buffet is served every morning in the rooftop breakfast room with city views. You can also access breakfast at the on-site Starbucks.
Yes. The hotel has an on-site restaurant that serves traditional Roman and classic Italian dishes, along with a selection of wines and champagne. Lunch and dinner are available.
Yes. Free WiFi is available in the rooms, and internet access is offered throughout the property.
Yes. The hotel is wheelchair accessible and includes facilities for disabled guests. Accessible features include a toilet with grab rails and a bathroom emergency cord.
It is a 10-minute walk from Castel Sant'Angelo and the historic center, and a 15-minute walk from the Vatican and Saint Peter's Basilica. Lepanto Metro Station is 1476 feet away.
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