Hilton Jacksonville At Mayo Clinic | Hotel in Southside, Jacksonville
Southside mornings, warm light, a kitchen for longer stays.
Located in Little Italy, Kasa Little Italy puts the neighborhood’s cafes, galleries, and waterfront right outside the door. Amtrak’s Santa Fe Depot is a 6-minute walk away, San Diego International is a quick 7-minute drive, and the USS Midway Museum is just 9 minutes from your suite.Once you get back, unwind on the balcony most units feature, or head down to the pool and fitness center for a change of scenery. Every suite comes with free WiFi, a flat-screen TV, and cashless, contactless self check-in via the virtual front desk. A private bathroom, single-room air conditioning, and a full kitchen are featured in every 42–91 m² suite or studio. King beds furnish the 1-bedroom suites, while studios pair a queen with a sofa bed, and select studios add a soaking bathtub. Full toiletries are stocked throughout, and thanks to the in-unit washer and dryer, you’ll be able to travel light.
24-hour front desk, air conditioning, Jacksonville Beach Golf Club 5.1 miles away

- Arrival
- Minimum check-in age 21, photo ID and credit card
- Design
- Desk in each room, air conditioning
- Bath products
- Raised toilet, Toilet with grab rails
- Tech
- Free Wifi, flat-screen TV, business center
Rooms with desks, fridges, and simple daily function
An outdoor pool, a fitness center, and a terrace outside
Hilton Jacksonville At Mayo Clinic Reviews
Overall everything was great.
Good to know · before you book.
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Frequently asked questions
Yes. Parking is available on site, and there is also an electric vehicle charging station and accessible parking.
Yes. Free WiFi is available throughout the property.
Yes. Breakfast is available, with à la carte, Full English/Irish, or American options.
Yes. There is an outdoor pool.
No. Pets are not allowed.
Yes. The property has wheelchair accessible features, including facilities for disabled guests, a raised toilet, lowered sink, and toilet with grab rails.
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