Stay well, then step out and discover Southern Region.
Best Stays by Sonder Southern Region
Find places to stay in Southern Region. Choose from apartment-style stays and boutique hotels for weekend breaks, business trips, and longer city stays.
Travelers
Old streets, downtown mornings, foothill air.
From Charleston's dinner streets to Greenville's walkable downtown and Columbia's central pace, start with the city that puts you closest to the Southern Region you came for.
Find the right kind of stay.
From boutique hotels in the middle of everything to apartment-style stays built for settling in, browse South Carolina by the kind of place that fits your trip.
Rooms with a view of the Southern Region you came for.
A small, curated edit of stays across South Carolina, old town and downtown, apartment and boutique hotel, to show the range before you narrow by city or region.
Sonder hasn't arrived in Southern Region yet. You may like these stays from trusted partners
-
Private Beach -
Oceanfront -
Hot Tub -
EV Charge Station
-
Parking -
Balcony/Terrace -
Kitchen -
Internet
-
Hot Tub
-
Parking
-
Balcony/Terrace
-
View
Southern Region travel questions, answered.
Quick answers to the questions travelers ask most.
If you are looking for a family-friendly vacation home in Southern Region, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Southern Region:
Currently, the total number of properties listed in 2026 is over 791 in the Southern Region area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Southern Region.